1,2-Benzenedicarboxylic acid di-C9-11-branched alkyl esters C10-rich Property

Density 

0.965 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.486

storage temp. 

Refrigerator

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Oil

color 

Colorless

CAS DataBase Reference

68515-49-1(CAS DataBase Reference)

EPA Substance Registry System

C10-Rich di-C9-11-branched alkyl phthalates (68515-49-1)

Safety

WGK Germany 

1

RTECS 

TI1270000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

1,2-Benzenedicarboxylic acid di-C9-11-branched alkyl esters C10-rich Chemical Properties,Usage,Production

Chemical Properties

The empirical formula of diisodecyl phthalate (DIDP) is C28H46O4. The structural formula of DIDP varies because the iso-alcohols used in the manufacture contain several isomers. DIDPis insoluble in water, but it is soluble in organic solvents.

Uses

It is a high-molecular-weight, general-purpose plasticizer that is added to polyvinyl chloride to impart flexibility.

Definition

ChEBI: Diisodecyl phthalate is a phthalate ester and a diester. Used as plasticizer for polyvinyl chloride in calendered film, coated fabrics, building wire jackets, wire and cable extrusion, and other applications.

Production Methods

DIDP is manufactured by the esterification of phthalic anhydride with isodecyl alcohol in the presence of a catalyst.

Flammability and Explosibility

Non flammable

Carcinogenicity

A 2-year bioassay was conducted in which DIDP was administered in the diet at concentrations of 400, 2000, and 8000 ppm to F344 rats. Rats of both sexes exhibited significant decreases in overall survival and body weights and increases in the relative weights of kidneys and liver with 8000 ppm of DIDP. No treatment-related neoplastic lesions were observed in the internal organs, including the liver. In addition, measurement of catalase enzyme activity, a marker for cell peroxisome proliferating activity, suggests that DIDP can induce peroxisome proliferation at an early stage (12 weeks of treatment) but fails to maintain the catalase-inducing potential by 32 weeks of treatment. An increased incidence of MNCL was observed in this study, butMNCLis a common neoplasm in F344 rats; the observed increased incidence is likely to be a species-specific effect with little or no relevance to humans. Therefore, DIDP was not considered to be carcinogenic at doses up to 8000 ppm in rats.